- Jayesh P, Kim B.-M, Jeong C.-B, Kim D.-H, Kang H.-M, Han J, Lee J.-S, (2017). Nine co-localized cytochrome P450 2N, 2AD and 2P gene family in the genome of mangrove killifish Kryptolebias marmoratus: Identification and expression in response to B[α] P, BPA, OP, and NP. Aquat. Toxicol. 187, 132-140. view
Fisheries and aquaculture sectors in India are vital sectors of food production, providing nutritional security not only to the weaker section of the society but also to other classes of communities irrespective whether rich or poor.Even though aquaculture production is increasing, the question remains whether the industry can continue to grow in a sustainable manner and to meet the future projected fish demand.Local aquaculture practices alone cannot meet the ever-widening demand-supply deficit resulting from the exponential increase in human population, therefore, there is need for new and improved scientific methods. So, a significant increase in productivity will now only be achieved through the adoption of genetic technologies. Many approaches to fish genetics, breeding, and genomics (structural to functional genomics) and their application in developing genetically enhanced fish species with desirable traits are included in this research area.To create high-yielding candidate species with certain quality features, fresh strategies are needed (QT). The development of a CRISPR-based platform for genome editing in fishes and a standardized procedure for germ-line transmission is the probable outcome of this exertion.
Vertical Zebra fish maintenance system with controlled environment
Gene transfer using microinjection in fish embryos and cell lines
Gene transfer using Lipofection in fish embryos and cell lines
Fish Embryo Cells
Work Elements
- Standardization of sex reversal, induced breeding in fishes
- Standardization of cryopreservation of fish embryos
- Development of Embryonic stem cells from fishes
- Characterization of the developed ES cells
- CRISPR / Cas9 based genome editing
- Germline transmission, developmental biology and assessment of genetic improvement
Research Projects
- Optimization of Genome Editing for Loss of function study in Danio rerio DRE/DRF cell line using RNA-guided Cas9 nucleases
- Development of CRISPR/Cas9 engineering platform for genome editing in Danio rerio and generation of mstn-knock-out lines
- Establishment of embryonic stem (ES) cells from Orange-spotted grouper (Epinephelus coioides) as germline transmission platform, and strain improvement through genome editing
Research Publications
- Aswathy C, Jayesh Puthumana, Valsamma Joseph (2022) “Development of host specific bicistronic vector system for CRISPR/Cas9 genome editing in Danio rerio”. 34th Kerala Science Congress.
Focus Areas
- Induced breeding
- Cryopreservation of fish embryos
- Embryonic stem cell development
- Genome editing
- Genetic improvement
Collaborating Institutes
Bharathidasan University C Abdul Hakeem CollegeOur Team
Dr. Jayesh P.
Aswathy C.
Dr. Prem Kumar, a Senior Scientist in the Finfish Culture Division at the ICAR-Central Institute of Fisheries Education (ICAR-CIFE), is recognized for his contributions to finfish aquaculture and sustainable fish farming practices. His research focuses on advancing breeding, seed production, and grow-out techniques for economically important finfish species, essential for enhancing fish farming efficiency and profitability. Dr. Kumar has been instrumental in developing improved methods for breeding and rearing native fish species, supporting biodiversity conservation while boosting aquaculture productivity in India.
Dr. David Verner-Jeffreys is a Senior Scientist at WorldFish and an esteemed expert in aquatic animal health and aquaculture biosecurity. With a background in fish pathology and disease management, Dr. Verner-Jeffreys has dedicated his career to developing solutions that enhance disease prevention and sustainable health practices in aquaculture systems globally. His research focuses on combating infectious diseases that impact fish farming, particularly in developing countries, where aquaculture plays a crucial role in food security and livelihoods.
Dr. M. Shashi Shekhar, is a distinguished expert in aquatic animal health and environmental management in brackishwater aquaculture. With extensive experience in fish and shrimp health management, his work addresses critical challenges in disease prevention, environmental sustainability, and biosecurity, contributing to the growth and resilience of India’s brackishwater aquaculture sector. By emphasizing biosecurity, environmental monitoring, and eco-friendly health management practices, Dr. Shekhar has contributed to enhancing the resilience and sustainability of shrimp and fish farming.
Dr. K.V. Rajendran is a prominent aquaculture scientist at the ICAR-Central Institute of Fisheries Education (ICAR-CIFE) in India, recognized for his expertise in fish health management and aquatic animal disease control. With a focus on advancing disease diagnostics, biosecurity, and sustainable health practices in aquaculture, Dr. Rajendran’s work has greatly contributed to improving the resilience and productivity of India’s aquaculture sector. His research addresses major challenges related to fish and shellfish health, particularly in diagnosing and managing viral, bacterial, and parasitic diseases that impact farmed species.
Dr. T. Raja Swaminathan is a renowned scientist at the ICAR-Central Institute of Fisheries Technology (ICAR-CIFT) in Kochi, India, with expertise in fish health management, aquaculture biosecurity, and disease diagnostics. His work focuses on addressing challenges related to aquatic animal health, particularly in ensuring sustainable and safe practices in India’s aquaculture industry. Dr. Swaminathan is recognized for his contributions to the detection and control of fish and shellfish diseases, which are critical for enhancing productivity and reducing economic losses in aquaculture.
Dr. Neeraj Sood, a distinguished scientist at the ICAR-National Bureau of Fish Genetic Resources (ICAR-NBFGR) in India, is recognized for his work in fish genetics, conservation, and sustainable aquaculture practices. His research focuses on the genetic characterization and conservation of fish biodiversity, which is critical for protecting valuable genetic resources and promoting sustainable aquaculture. By identifying and cataloging fish species and their genetic diversity, Dr. Sood has contributed to the preservation of native fish species, ensuring that these resources can support resilient and productive aquaculture systems in India.
Dr. B. Santhosh, a leading scientist at the Vizhinjam Regional Centre of the ICAR-Central Marine Fisheries Research Institute (ICAR-CMFRI), is known for his impactful contributions to marine aquaculture and coastal fisheries development in India. His work focuses on advancing sustainable practices in mariculture, particularly in seed production, hatchery technology, and the cultivation of high-value marine species like finfish, shellfish, and sea cucumbers. Dr. Santhosh’s research has played a critical role in supporting livelihood opportunities for coastal communities by promoting aquaculture as a viable and environmentally sustainable industry.
Dr. Victoria Alday-Sanz is a renowned aquaculture expert at National Aquaculture Group (NAQUA) in Saudi Arabia, recognized globally for her work in shrimp health management, biosecurity, and sustainable aquaculture practices. With a background in veterinary science and extensive experience in aquatic animal health, Dr. Alday-Sanz has played a critical role in advancing shrimp farming practices to enhance productivity while maintaining rigorous biosecurity standards. Her work is instrumental in addressing major health challenges in shrimp aquaculture, particularly in the prevention and management of viral and bacterial diseases that can impact large-scale operations.
J.M.P.K. Jayasinghe is a distinguished figure in aquaculture, known for his contributions to sustainable fish farming practices, particularly in Asia. With a focus on innovative aquaculture technologies and resource management, he has dedicated his career to improving the productivity, efficiency, and environmental sustainability of aquaculture systems. Jayasinghe has been involved in developing best practices that help small-scale and commercial farmers enhance yields while minimizing the environmental impact, which is crucial for both economic growth and ecological health.
Dr. Vasant Kripa is the former Secretary of the Coastal Aquaculture Authority (CAA) in Chennai, India, and a highly respected scientist in marine biology, coastal aquaculture, and environmental management. With a career spanning over three decades, Dr. Kripa has been instrumental in developing policies and practices that promote sustainable and responsible coastal aquaculture in India. Her work has focused on balancing the growth of aquaculture with environmental conservation, ensuring that coastal ecosystems remain resilient and productive.
Dr. K.M. Shankar is the Vice Chairman of the Asian Fisheries Society, Indian Branch, and former Dean of the College of Fisheries in Mangalore, India. A highly respected figure in fish health management and aquaculture, Dr. Shankar has contributed significantly to advancing aquaculture science, particularly in aquatic animal health, biotechnology, and sustainable fisheries. His research focuses on pathogen detection, disease management, and biosecurity in aquaculture, addressing key challenges to improve productivity and sustainability in the industry.
Prof. Arun K. Dhar is a Professor and Director of the Aquaculture Pathology Laboratory at the School of Animal & Comparative Biomedical Sciences, The University of Arizona, USA. An expert in aquaculture pathology and virology, Prof. Dhar is highly regarded for his research on diseases affecting shrimp and other aquatic species. His work focuses on identifying, understanding, and managing viral pathogens that pose significant threats to aquaculture industries globally.
Dr. Iddya Karunasagar is a distinguished Indian microbiologist and food safety expert, known for his pioneering work in aquatic microbiology, aquaculture health, and public health. His research focuses on seafood safety and disease management in aquaculture, with significant contributions to understanding and controlling microbial pathogens, such as Vibrio species, which affect marine organisms. His work has helped develop diagnostic tools and strategies that promote sustainability in aquaculture and ensure safer seafood.
Dr. Pramoda Kumar Sahoo is the Director-cum-ICAR National Professor at the Indian Council of Agricultural Research-Central Institute of Freshwater Aquaculture (ICAR-CIFA). A leading expert in fish health management and aquatic animal diseases, Dr. Sahoo’s work focuses on advancing disease control, immunology, and molecular biology in freshwater aquaculture. His research is pivotal in improving the health, resilience, and sustainability of India’s aquaculture industry, which plays a vital role in food security and rural livelihoods.
Dr. Rohana Subasinghe is the Managing Director of FutureFish, a consultancy specializing in sustainable aquaculture and fisheries development. With over 30 years of experience in aquaculture, aquatic animal health, and international fisheries, Dr. Subasinghe is a globally recognized expert dedicated to promoting sustainable practices that support food security, environmental protection, and socioeconomic growth.
Dr. Eduardo Leano is the Director General of the Network of Aquaculture Centres in Asia-Pacific (NACA), an intergovernmental organization focused on sustainable aquaculture development in the Asia-Pacific region. With a strong background in aquatic animal health and pathology, Dr. Leano has dedicated his career to advancing sustainable aquaculture practices, improving disease management, and promoting biosecurity within the industry.